•       Outstanding sensitivity enables detailed characterization and optimization of lead compounds, even for difficult targets where response levels are low

•       Screen 384 fragments in less than a day

•       Run competition assays or scout for optimal buffers directly from microplates

Biacore S200 is our most sensitive SPR-based sensor for cutting-edge applications and offers exceptional data quality using small sample volumes. Predefined run and evaluation templates guide the user and shorten time to results. The templates are available for all major types of assay and are preloaded with application-relevant settings. The templates are fully flexible and can be easily adjusted to fit specific assay needs. In addition to direct binding assays you can identify site-selective binders directly using competition assay.

Analysis of complex proteins made easy

High sensitivity is achieved thorugh a combination of the low baseline noise and the fast data collection rate, which enables analysis of very fast off-rates. The high sensitivity reduces the risk of secondary interactions and makes analysis of multidomain and rare/sensitivie protein interactions possible

Realize the potential of competition analysis with SPR

Biacore S200 simplifies the setup of comeptiton experiment using a novel injection method that reduces the consumption of competitor and allows validation of binders for binding-site mapping.

Discover more about the interaction

Thermodynamic analysis enables prediction of binding energetics from the 3D structure of protein complexes, providing deeper understanding of molecular interactions. The forces driving the interaction are revealed through dedicated software templates, built-in buffer degassing, and stringent temperature control.